Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

Then there were these cautionary tales, where a candidate
Overall, state-owned and private businesses invested an unprecedented $23bn in Europe — including Norway and Switzerland as well as the EU — in 2015 while investing $15bn in the US, according to a report by Baker & McKenzie, a lawfirm, and Rhodium Group, a consultancy.
They also arrived 40 minutes late for the official welcome and were running late to an event in Vancouver, too.
此次涵盖95个项目(去年为90个)的排行榜中,来自7个国家的9所院校为首次进入榜单。排名第41位的法兰克福金融管理学院(Frankfurt School of Finance & Management)是今年排名最高的新入榜者。这家德国学院拥有性别比例最平衡的项目之一,女性占学员总数的49%。
评委会将奖项授予了来自东京工业大学的大隅良典,以表彰他在细胞自噬作用研究上所做的贡献。
5.Debrecen, Hungary
It was in Giambattista Valli’s most recent autumn-winter show, full of puffed-sleeve printed tunics over matching trousers and drop-waisted schoolgirls shifts, and in MaxMara’s ode to Marilyn Monroe’s 1962 photo shoot with George Barris.
Until a couple of games ago, Stephen Curry really hadn't thought much about making more NBA history.
remembrance
The report also showed regions with a better-developed economy produce more cyberstars, with Beijing, Shanghai, Guangdong, Jiangsu and Zhejiang leading the rankings.
Atlas Wearables founder Peter Li says battery technology and user retention are two more obstacles facing the wearables market. Some use cases require significant improvements to battery technology for a compelling experience, he says, and there’s always a balance to be struck between wear time between charges and processing power and features.
服务业增加值占国内生产总值比重上升到51.6%;
James Franco’s new movie about the making of The Room will make you belly-laugh, but its comedy is also deeper and richer than mere mockery.
“The Big Short” (Adam McKay)
comedy
Wearables typically fall into three categories: complex devices such as fitness trackers; smart accessories such as smart watches, defined by their ability to run third-party applications; and fully autonomous smart wearables that connect directly to the Internet, such as Google’s Glass headset.
We learned that there is new hope for Africans with treatable cancers.
Saif held the highest position among the five ranked Chinese schools, just ahead of Guanghua School of Management and Tsinghua University School of Economics and Management, 17th and 18th respectively.
第一种看法是,油价本质上具有周期性。下跌之后必然会回升。这道波谷越深,下一个山峰就越高。
在Ross居住的单元,不准记者入内,一名妇女在门缝中礼貌的说,孩子的母亲还没有准备好公开发言。
"My hair has turned white, half because of housing prices and half because of you reporters." JIANG WEIXIN, member of the CPPCC National Committee and minister of housing and urban-rural development, responding to media questions about government measures to curb housing prices
n.
事实上,去往俄罗斯有许多可供选择的廉价航班。其国内的西伯利亚大铁路也使得交通十分便利。
"The editors thought the articles were being sent out to genuine reviewers in the discipline," he said. "Following our investigation and communication with the real reviewers, they confirmed they did not conduct the peer review."
General Motors is helping fuel the improved jobs outlook in the Grand Canyon State. In March, the automaker announced plans to build the company’s fourth Information Technology Innovation Center in Phoenix suburb Chandler. GM is expected to hire 1, 000 workers, mainly consisting of software developers, database administrators and systems analysts for the new center. “The greater Phoenix area is a fantastic hub of emerging technical talent – from university graduates to working professionals, ” said GM CIO Randy Mott in a release announcing the move.


单词facilitate 联想记忆:
I empathize with the Mavs' position. It's tough to tell your fans that all hope is lost in November, and it's especially tough when you've got a Hall of Famer still on your roster.
据德国工商总会的数据显示,法国在2016年继续保持德国第二大贸易伙伴的地位。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

顺便说一句,伦敦的自行车租赁制度再简单不过了:走到任何一个租车点,刷卡付费就可以带走一辆自行车。当你使用完毕时,把车丢在附近的河里就行。这些自行车都是一次性的!
与此同时,预计出口将继续下降,原因是全球需求疲软而价格上涨,以及中国实际上决定让人民币汇率再度盯住正在走强的美元。
我立刻赞同了克雷格和尼尔关于艾伦是今年颁奖礼最合适的主持的想法。我们希望举办一场娱乐、吸引人而又有趣的颁奖礼。
他说:“小说忠于邦德的人物形象,邦德还是粉丝喜欢的、那个最初的硬汉邦德。”

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

值得庆幸的是,这些户籍规定正在发生改变。12月初,在中国中央经济工作会议上,与会代表建议给予农村居民城市户口,这也强有力地证明了户籍制度正在变化。温家宝总理于12月底呼吁,应加快户籍制度改革的进程。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Batman vs Superman: Dawn of Justice is scheduled to hit theatres on March 23, 2016.
鲜菜价格同比上涨13%,助推食品价格同比上涨3.7%,涨幅比上月扩大0.5个百分点。

林怡仲预测道,下半年A股IPO的数量或将维持与上半年相当,预计2016年全年A股IPO为120宗左右,融资规模在600-800亿元人民币左右。
威尔·史密斯早年成名,那是上世纪80年代末90年代初,他做嘻哈组合"DJ爵士杰夫&活力王子"的后期成员时。然而,虽然他赚得盆满钵盈,却不善于管理金钱。这真是个老掉牙的故事。名望、金钱扑面而来;却没有远见,空有一堆玩物,最终导致超支。对财产的监管意识与责任感的缺失,让他从富有的顶峰一下跌到破产的边缘。没落之后,他欠政府的退缴税一直没能偿还。
IFAD的政策顾问、这篇报告的作者佩德罗·德·瓦斯孔塞卢斯称:“这确实是一个全球性的现象,由于缺乏机会,人们不得不背井离乡,出门打工养活家人。”
Meanwhile, the University of Bradford School of Management and the University of Edinburgh Business School each climb 16 places, to 42nd and 55th, respectively. Judge Business School at the University of Cambridge rises 15 places to 14th.
Bill Gates topped the list of the world's richest billionaires for the 17th time in 22 years, it has been revealed.
今年最佳的季中交易早已发生了:

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


2014家居行业标准化渐近 “正能量”保障消费者权益


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


来自中国首都北京的北京大学和清华大学,分列2017年亚洲大学排行榜的第二、三名。而新加坡国立大学则位居榜首。
The job market faces challenges. Some five million Americans have been out of work for six months, raising the risk their skills will erode and make it even harder for them to find jobs down the road. And fears of slowing revenue growth could keep a lid on hiring by companies. About 36% of U.S. executives expect the head count at their firm to fall, according to an October survey by advisory firm CEB, compared with 29% who said that during the summer.[qh]
Did you write The Lego Batman Movie off as kids-only? Biggest mistake ever. This movie is a witty feat of hilarity, full of dry humor and moments of comedy gold. Basically, if you like Will Arnett in Arrested Development, you will like this.
"Hong Kong is a small island with 7 million people ... and you have 1.5 billion across the border (in mainland China) who would like to invest," Mark Elliott, associate director of International Residential Property Services at Jones Lang LaSalle, tells CNN. "The government is releasing more and more land, but it doesn't work."
切实落实脱贫攻坚责任制,实施最严格的评估考核,严肃查处假脱贫、“被脱贫”、数字脱贫,确保脱贫得到群众认可、经得起历史检验。
其实,它体现在所有品牌上,它们把六七十年代的服装搬到当季店铺里,包括阿尔伯特·菲尔蒂(Alberta Ferretti)、璞琪(Pucci)和艾绰(Etro)。
The prices are tough for ordinary Brazilians to afford. The minimum wage in the country is $330 a month, just about what Ferreira said she earns.
单词combat 联想记忆:
He slipped a note through the door with the message "People stuck inside, please ask the property management for help," and hoped someone would pick it up and act on it.
The fastest-rising sector is apparel, driven by Nike in sportswear as people pay more attention to health and fitness, and Zara, whose fast fashion is becoming increasingly popular in China.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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要让Airbnb退市,可能没那么容易。最近,昆尼皮亚克大学(Quinnipiac)开展的一项民意调查表明,56%的受访者认为,应该允许纽约人将房间租给陌生人。“我们不想把房子变成旅馆,但是与此同时,人们有时会想把自己的公寓租出去。”霍尔斯特德管理公司(Halstead Management Company)的总裁保罗·R·戈特塞根(Paul R. Gottsegen)说。该公司打理着纽约市250处住宅物业。
At the same ceremony in New York, Dominic Barton, McKinsey’s global managing director, awarded the Bracken Bower Prize for young business writers to Christopher Clearfield and András Tilcsik. Their proposed book would look at how businesses can manage the risk of catastrophic failure. The 15,000 prize goes to the best proposal for a business book about the challenges and opportunities presented by growth by authors under 35.
The improvements in education levels mirrored the development of China's education system. Independent research into China's education situation showed that overall education development was better than the world average last year, Yuan Guiren, minister of education, said in March.
The Family Hub has three internal cameras that connect to your phone to help you see what you do and don't have inside the fridge. So it's basically a $6,000 alternative to classic grocery list written on paper with a pencil.

Comic skit “I Want To Be In Spring Festival Gala” (Various artistes)

  • Only the first three authors are listed, followed by "et al."
  • 2015年1-11月全国经济数据出炉 家具业原来是这样
  • 红木制造产业坏境污染 治理刻不容缓


The report provided in-depth observations on 28 Chinese business and administrative capitals - excluding Beijing and Shanghai - using several indicators.
与此同时,微信恐怕也是腾讯吸引海外用户潜力最大的产品。Forrester的分析师Bryan Wang说,他看到新加坡、印度的同事和朋友也开始出现在了自己的微信好友列表中。

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